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Anti-BF (Center) Antibody
Catalog #: 102-17300
Rabbit Anti-Human BF (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P00751 |
| Gene Id | 629 |
| Gene Symbols | CFB |
| Protein Name / Synonyms | BF (Center) |
| Clonality | Polyclonal |
| Preparation | This BF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 395-422 amino acids from the Central region of human BF. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
BF is complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation.
Specificity
Other Names
CFB; BF; BFD; Complement factor B; C3/C5 convertase; Glycine-rich beta glycoprotein; PBF2; Properdin factor B; Complement factor B Ba fragment; Complement factor B Bb fragment
NCBI Accession #
NP_001701.2
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
85533
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100
 | Western blot analysis of BF Antibody (Center) (Cat# 102-17300) in HepG2 cell line and mouse liver tissue lysates (35ug/lane). BF (arrow) was detected using the purified Pab. |
 | BF Antibody (Center) (RB18685) IHC analysis in formalin fixed and paraffin embedded human hepatocarcinoma tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the BF Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.