Anti-Bi-Phospho-GSK3B (S21/29) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse
Host Species	Rabbit
Accession Number	P49841
Gene Id	2932
Gene Symbols	GSK3B
Protein Name / Synonyms	Bi-Phospho-GSK3B(S21/29)
Clonality	Polyclonal
Preparation	This GSK3B Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S21/29 of human GSK3B.
Concentration (lot specific)	0.450 mg/ml
Recommended Applications	Western Blotting, IHC-P
Research Area	Cardiovascular Disease, Autophagy
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Glycogen synthase kinase-3 (GSK3) is a proline-directed serine-threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase. Two isoforms, alpha (GSK3A) and beta, show a high degree of amino acid homology. GSK3B is involved in energy metabolism, neuronal cell development, and body pattern formation.

Specificity

Other Names

GSK3B; Glycogen synthase kinase-3 beta; Serine/threonine-protein kinase GSK3B

NCBI Accession #

NP_001139628.1;NP_002084.2

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

46744

Recommended Dilutions

WB: 1:1000; IHC: 1:50-100

	The anti-Phospho-GSK3B-S21/29 Pab (Cat# 102-15303) is used in Western blot to detect Phospho-GSK3B-S21/29 in mouse thymus tissue lysate.
	Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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