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Anti-Bmp3 (N-term) Antibody
Catalog #: 102-13299
Rabbit Anti-Human Bmp3 (N-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P12645 |
| Gene Id | 651 |
| Gene Symbols | BMP3 |
| Protein Name / Synonyms | Bmp3 (N-term) |
| Clonality | Polyclonal |
| Preparation | This Bmp3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 8-36 amino acids from the N-terminal region of human Bmp3. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
The BMPs belong to the TGF-Beta superfamilyBMPs stimulate the production of bone matrix proteins and thereby alter stromal cell and osteoclast proliferation, a key step in bone marrow development. In addition to promoting ectopic bone and cartilage development, BMPs regulate the growth, differentiation, chemotaxis, proliferation, and apoptosis of various cell types, including mesenchymal cells, epithelial cells, hematopoietic cells, and neuronal cells. BMPs also play a role in dorsal/ventral patterning. BMP3, highly expressed in lung, ovary and small intestine, participates in cartilage and bone formation. BMP3 and BMP2 genes map to conserved regions between human and mouse.
Specificity
Other Names
BMP3; BMP3A; Bone morphogenetic protein 3; Bone morphogenetic protein 3A; Osteogenin
NCBI Accession #
NP_001192.2
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
53372
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100
 | Western blot analysis of hBmp3-E23 (Cat# 102-13299) in 293 cell line lysates (35ug/lane). BMP3 (arrow) was detected using the purified Pab. |
 | Western blot analysis of Bmp3 (arrow) using rabbit polyclonal Bmp3 Antibody (N-term) (Cat# 102-13299). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the Bmp3 gene (Lane 2) (Origene Technologies). |
 | Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.