3607 Parkway Ln Ste 200 Norcross, Georgia 30092
www.RayBiotech.com | info@raybiotech.com
770-729-2992 | +1-888-494-8555
ISO 13485:2016 cGMP
Anti-Bovine Granulysin Antibody
Catalog #: RB-06-0001
Rabbit Anti-Bovine Granulysin Antibody
Product Description
Specifications
| Size | 20 µg, 100 µg, 200 µg, 500 µg |
| Estimated Lead Time | 1-2 business days |
| Species | Bovine (cow) |
| Accession Number | NP_001068611 |
| Clonality | Polyclonal |
| Immunogen | Immunogen was synthetic peptide derived from bovine Granulysin. This antibody was produced from a rabbit immunized with the immunogen. The IgG fraction was purified from rabbit serum followed by Protein A/G affinity chromatography. |
| Immunogen Sequence | CVDIKMCKSKPVGFI |
| Recommended Applications | ELISA (recommended work dilution= 1 : 64, 000) |
| Reconstitution | Supplied as lyophilized and purified antibody originally containing PBS, without Preservative Stabilizers, such as Sodium Azide. The final concentration is indicated on the shipping vial. Please avoid freeze-thaw cycles. The antibody is stable for at least years from the data of receipt when stored at -20°C to -70°C. Reconstituted antibody (recommended with H20 1 mg/ml) can also be aliquoted and stored frozen at -20°C to -70°C in a manual defrost freezer for months without detectable loss activity. Upon reconstitution, the antibody can be stored at 4°C for 1 month. |
| Research Area | Cardiovascular Disease |
| Shipping Type | Ambient temperature |
| Storage | -20°C |
Description
Description
Granulysin is also called as Lymphokine LAG-2, Protein NKG5 and T-cell activation protein 519.The protein has been found in many species. It is belonged to antimicrobial protein because it can kill intracellular pathogens, including Gram-positive and Gram-negative bacteria, fungi, and parasites. Currently, one of the most interesting antimicrobial activities associated with granulysin is the ability to directly kill mycobacteria. In contrast to other antimicrobial peptides, such as defensins, granulysin is confined to the cytotoxic granules of NK cells and T lymphocytes. Bovine Granulysin, consisting of 146 amino acids is one of attractive anti-pathogen candidates.
Specificity
Rabbit anti-Bovine Granulysin antibody can specifically detect the synthetic peptide, but not unrelated peptides and proteins. Cross reactivity with other species has not yet been tested.
Storage
Store at -20°C, if not intended for use within a month, keep it at 4°C and minimize freezing and thawing when use.
References
- Krensky A.M. Granulysin: a novel antimicrobial peptide of cytolytic T lymphocytes and natural killer cells. Biochem. Pharmacol. 59:317-320(2000)
- Stenger S., et.al., An antimicrobial activity of cytolytic T cells mediated by granulysin. Science 282:121- 125(1998); Janice J. Endsley, et.al., Characterization of Bovine Homologues of Granulysin and NK-lysin. The Journal of Immunology, 173: 2607-2614(2004).
Expiration:
12 months from the date of shipment when stored properly.