Anti-BPGM (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P07738
Gene Id	669
Gene Symbols	BPGM
Protein Name / Synonyms	BPGM (C-term)
Clonality	Polyclonal
Preparation	This BPGM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 230-259 amino acids from the C-terminal region of human BPGM.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting
Research Area	Inflammation
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

2,3-diphosphoglycerate (2,3-DPG) is a small molecule found at high concentrations in red blood cells where it binds to and decreases the oxygen affinity of hemoglobin. This gene encodes a multifunctional enzyme that catalyzes 2,3-DPG synthesis via its synthetase activity, and 2,3-DPG degradation via its phosphatase activity. The enzyme also has phosphoglycerate phosphomutase activity. Deficiency of this enzyme increases the affinity of cells for oxygen. Mutations in this gene result in hemolytic anemia. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Specificity

Predicted Reactivity

Monkey

Other Names

BPGM; Bisphosphoglycerate mutase; 2,3-bisphosphoglycerate mutase, erythrocyte; 2,3-bisphosphoglycerate synthase; 2,3-diphosphoglycerate mutase; BPG-dependent PGAM

NCBI Accession #

NP_001715.1;NP_954655.1

Other Accession #

Q4R6L7; NP_954655.1; NP_001715.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

30005

Recommended Dilutions

WB: 1:1000

	BPGM Antibody (C-term) (Cat# 102-11658) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the BPGM antibody detected the BPGM protein (arrow).
	Western blot analysis of BPGM (arrow) using rabbit polyclonal BPGM Antibody (C-term) (Cat# 102-11658). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the BPGM gene.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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