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Anti-BRAP Antibody
Catalog #: 102-26569
Mouse Anti-BRAP Antibody, 100 µl
Product Description
Specifications
| Size | 100 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Mouse |
| Accession Number | Q7Z569 |
| Gene Id | 8315 |
| Gene Symbols | BRAP |
| Protein Name / Synonyms | 3010002G07Rik;BRAP2;BRCA1 associated protein;EC 6.3.2.;Galectin 2 binding protein;I |
| Clonality | Monoclonal |
| Recommended Applications | Western Blotting |
| Research Area | Ras/Rap Signaling |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
Negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. Also acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto- polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation. May also act as a cytoplasmic retention protein with a role in regulating nuclear transport.
Other Information
Antigen Type
Recombinant Protein
Images
WB (1:1000)
Western blot analysis of extracts from CHO-K1 cells, transfected with a human pFLAG-CMV2-BRAP construct (A) or transfected with a human pFLAG-CMV2 construct (B), using BRAP mouse mAb (1:1000 diluted).
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.