Rabbit Anti-Human BRD2 (Center) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P25440 |
| Gene Id | 6046 |
| Gene Symbols | BRD2 |
| Protein Name / Synonyms | BRD2 (Center) |
| Clonality | Polyclonal |
| Preparation | This BRD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 170-200 amino acids from the Central region of human BRD2. |
| Concentration (lot specific) | 2.000 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
BRD2 is a mitogen-activated kinase which localizes to the nucleus. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3 but sequence comparison suggests that the protein is not involved in the immune response. Homology to the Drosophila gene female sterile homeotic suggests that this human protein may be part of a signal transduction pathway involved in growth control.
Specificity
Predicted Reactivity
Mouse, Rat, Bovine
Other Names
BRD2; KIAA9001; RING3; Bromodomain-containing protein 2; O27.1.1; Really interesting new gene 3 protein
NCBI Accession #
NP_001106653.1;NP_001186384.1;NP_001186385.1;NP_005095.1
Other Accession #
Q6MGA9; Q7JJ13; Q32S26
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
88061
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100
 | BRD2-Q185 (Cat# 102-17775) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the BRD2 antibody detected the BRD2 protein (arrow). |
 | Western blot analysis of BRD2 (arrow) using rabbit polyclonal BRD2 Antibody (Center) (Cat# 102-17775). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the BRD2 gene (Lane 2) (Origene Technologies). |
 | Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.
