Rabbit Anti-Human BTK (N-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q06187 |
| Gene Id | 695 |
| Gene Symbols | BTK |
| Protein Name / Synonyms | BTK (N-term) |
| Clonality | Polyclonal |
| Preparation | This BTK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-55 amino acids from the N-terminal region of human BTK. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Research Area | Cancer |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement.
Specificity
Predicted Reactivity
Mouse, Chicken
Other Names
BTK; AGMX1; ATK; BPK; Tyrosine-protein kinase BTK; Agammaglobulinaemia tyrosine kinase; B-cell progenitor kinase; Bruton tyrosine kinase
NCBI Accession #
NP_000052.1
Other Accession #
P35991; Q8JH64; NP_000052.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
76281
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
 | BTK Antibody (N-term) (Cat# 102-12051) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the BTK antibody detected the BTK protein (arrow). |
 | Western blot analysis of BTK (arrow) using rabbit polyclonal BTK Antibody (N-term) (Cat# 102-12051). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the BTK gene. |
 | BTK Antibody (N-term) (Cat# 102-12051)immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of BTK Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.