C3a is an anaphylatoxin derived from proteolytic degradation of complement C3 that increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.

This product recognizes recognizes a C3a-determinant which is present also on native C3. This product allows discrimination of ubiquitous or nonspecifically bound native C3 from biologically active C3b fragment, C3b or C are negative with this product.

This product is reported to block C3a functional activity.

C3a