Anti-C8 Antibody

Catalog #: DS-MB-02783

Mouse Anti-Human C8

Product Description

Specifications

Size	0.1 mg
Estimated Lead Time	1-2 weeks
Species	Human
Specificity	This product recognizes complement component 8 (C8), a 151 kDa member of the complement C6/C7/C8/C9 family, present in blood serum. C8 is a terminal component of the complement system, part of both the complement membrane attack complex (MAC), and important to MAC assembly. C8 binds to the C5b-7 complex, anchored to the membrane, creating C5b-8. C5b-8 binds C9 and catalyses the polymerization of C9 molecules to form C5-b9 (MAC). C8 is thought to contain lipid binding sites, facilitating the insertion of MAC into the membrane. Defects in the alpha chain of C8 can result in complement C8 deficiency type I. Furthermore, C8 deficiencies can cause recurring bacterial infections, in particular from Neisseria meningitides.
Host Species	Mouse
Protein Name / Synonyms	C8
Concentration (lot specific)	IgG concentration 1.0mg/ml
Recommended Applications	Immunohistology - Frozen, ELISA, Flow Cytometry, Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Storage/Stability

Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:

Purified IgG - liquid

Formulation:

Borate buffered saline

Format Type:

Purified

Preparation

Immunogen:

Purified human C8

Preservative:

0.1% Sodium Azide (NaN₃)

Expiration:

12 months from the date of shipment when stored properly.

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