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Anti-Calcitonin Antibody
Catalog #: 130-00025
Rabbit Anti-Human Calcitonin Antibody
Product Description
Specifications
| Size | 20 µg, 100 µg, 200 µg, 500 µg |
| Estimated Lead Time | 1-2 business days |
| Species | Human |
| Accession Number | P01258 |
| Gene Id | 796 |
| Gene Symbols | CALCA CALC1 |
| Clonality | Polyclonal |
| Immunogen | Immunogen was recombinant protein derived from human calcitonin. This antibody was produced from a rabbit immunized with the immunogen. The IgG fraction was purified from rabbit serum followed by Protein A/G affinity chromatography. |
| Immunogen Sequence | CMLGTYTQDFNKFHTFPQTAIGVGA |
| Recommended Applications | ELISA (recommended work dilution= 1: 2, 000-4, 000), Western Blotting (recommended work dilution= 1: 1, 000-2, 000) |
| Reconstitution | The purified antibody is supplied lyophilized originally containing PBS without any preservative stabilizers. The final amount is indicated on the shipping vial. The lyophilized antibody is stable for at least a year from the date of receipt when stored frozen at -20°C to -70°C. It is suggested that the antibody is reconstituted with sterile water and can be aliquoted and stored frozen at -20°C to -70°C in a manual defrost freezer for months without detectable loss of activity. Upon reconstitution, the antibody can also be stored for months at 4°C. |
| Research Area | Cancer |
| Shipping Type | Ambient temperature |
| Storage | -20°C |
Description
Description
Calcitonin is a hormone. Mature calcitonin is composed of 116 amino acids and plays an important role in calcium homeostasis. Calcitonin is mainly produced by parafollicular C cells of the thyroid and the endocrine cells of the intestine and lung. Calcitonin causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.
Specificity
The antibody can specifically bind to its immunogen, and did not show any cross reactivity with unrelated antigens in ELISA. It also could specifically recognize recombinant protein, cellular protein as assayed by Western Blot. Cross reactivity with mouse and rat procalcitonin has not yet been tested.
Storage
The lyophilized antibody may be stored at 4°C if intended for use within a month. Please store at -20°C for longer term storage. Minimize freeze-thaw cycles.
Expiration:
12 months from the date of shipment when stored properly.