Anti-CAMK2A (C-term E370) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q9UQM7
Gene Id	815
Gene Symbols	CAMK2A
Protein Name / Synonyms	CAMK2A (C-term E370)
Clonality	Polyclonal
Preparation	This CAMK2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 344-371 amino acids from the C-terminal region of human CAMK2A.
Concentration (lot specific)	2.000 mg/ml
Recommended Applications	Western Blotting, IHC-P
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

CAMK2A belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by the gene for CAMK2A is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity.

Specificity

Predicted Reactivity

Mouse, Rat

Other Names

CAMK2A; CAMKA; KIAA0968; Calcium/calmodulin-dependent protein kinase type II subunit alpha

NCBI Accession #

NP_741960.1

Other Accession #

P11275; P11798

Format

Type

Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

54088

Recommended Dilutions

WB: 1:1000; IHC: 1:10-50

	Western blot analysis of anti-CAMK2A Antibody (C-term E370) (Cat# 102-17335) in 293 cell line lysates (35ug/lane). CAMK2A(arrow) was detected using the purified Pab.
	Western blot analysis of CAMK2A (arrow) using rabbit polyclonal CAMK2A Antibody (C-term E370) (Cat# 102-17335). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CAMK2A gene (Lane 2).
	Formalin-fixed and paraffin-embedded human brain tissue reacted with CAMK2A (C-term E370) (Cat# 102-17335), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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