Anti-CAMK2D (CAMK2 delta) (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human, Non-Human Primate (rhesus monkey)
Host Species	Rabbit
Accession Number	Q13557
Gene Id	817
Gene Symbols	CAMK2D
Protein Name / Synonyms	CAMK2D (CAMK2 delta) (C-term)
Clonality	Polyclonal
Preparation	This CAMK2D (CAMK2 delta) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 448-478 amino acids from the C-terminal region of human CAMK2D (CAMK2 delta).
Concentration (lot specific)	1.980 mg/ml
Recommended Applications	Western Blotting, IHC-P
Research Area	Cardiovascular Disease
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

CaM-kinase II (CAMK2) is a prominent Ser/Thr protein kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Likely autophosphorylation of Thr-286 allows the kinase to switch from a calmodulin-dependent to a calmodulin-independent state. CAMK2 is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. Expression of CAMK2 delta is significantly increased in patients suffering from dilated cardiomyopathy.

Specificity

Predicted Reactivity

Mouse, Pig, Rabbit

Other Names

CAMK2D; CAMKD; Calcium/calmodulin-dependent protein kinase type II subunit delta

NCBI Accession #

NP_001212.2;NP_742112.1;NP_742113.1;NP_742125.1;NP_742126.1;NP_742127.1

Other Accession #

O77708; Q95266; Q6PHZ2

Format

Type

Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

56369

Recommended Dilutions

WB: 1:1000; IHC: 1:50-100

	The anti-CAMK2delta C-term Pab (Cat# 102-17184) is used in Western blot to detect CAMK2 delta in serum-starved HeLa cell lysate.
	Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
	Formalin-fixed and paraffin-embedded human brain tissue reacted with CAMK2 delta Antibody (C-term) (Cat# 102-17184), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

Featured Products