Anti-CAT (Center) (Ascites) Antibody

Product Description

Specifications

Size	0.1 mL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse
Accession Number	P04040
Gene Id	847
Gene Symbols	CAT
Protein Name / Synonyms	CAT (Center) (Ascites)
Clonality	Monoclonal
Preparation	This CAT antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 152-180 amino acids from the Central region of human CAT.
Recommended Applications	Western Blotting
Research Area	Oxidative Stress
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene.

Specificity

Predicted Reactivity

Rat, Zebrafish, Bovine, Pig

Other Names

CAT; Catalase

NCBI Accession #

NP_001743.1

Other Accession #

P04762; O62839; P24270; Q9PT92; P00432; NP_001743.1

Format

Type

Mouse Monoclonal Antibody (Mab)

Calculated Molecular Weight (Da)

59756

Recommended Dilutions

WB: 1:100-1600

	CAT Antibody (Center)(Ascites)(Cat# 102-10344) western blot analysis in mouse Liver tissue lysates (35ug/lane).This demonstrates the CAT antibody detected the CAT protein (arrow).
	CAT Antibody (Center) (Ascites)(Cat# 102-10344) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the CAT antibody detected the CAT protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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