Anti-CBX1 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P83916
Gene Id	10951
Gene Symbols	CBX1
Protein Name / Synonyms	CBX1 (C-term)
Clonality	Polyclonal
Preparation	This CBX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 128-155 amino acids from the C-terminal region of human CBX1.
Concentration (lot specific)	0.25 mg/ml
Recommended Applications	Western Blotting, IHC-P, FC
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

CBX1 is a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression.

Specificity

Predicted Reactivity

Mouse

Other Names

CBX1; CBX; Chromobox protein homolog 1; HP1Hsbeta; Heterochromatin protein 1 homolog beta; Heterochromatin protein p25; M31; Modifier 1 protein; p25beta

NCBI Accession #

NP_001120700.1;NP_006798.1

Other Accession #

P83917

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

21418

Recommended Dilutions

WB: 1:1000; IHC: 1:50-100; FC: 1:10-50

	Western blot analysis of CBX1 Antibody (C-term) (Cat# 102-18075) in MCF-7, A2058, Y79 cell line lysates (35ug/lane). CBX1 (arrow) was detected using the purified Pab.
	CBX1 Antibody (C-term) (Cat# 102-18075) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CBX1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
	CBX1 Antibody (C-term) (Cat# 102-18075) flow cytometric analysis of MCF-7 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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