Anti-CBX5 (Center) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P45973
Gene Id	23468
Gene Symbols	CBX5
Protein Name / Synonyms	CBX5 (Center)
Clonality	Polyclonal
Preparation	This CBX5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-117 amino acids from the Central region of human CBX5.
Concentration (lot specific)	0.280 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Specificity

Predicted Reactivity

Mouse

Other Names

CBX5; HP1A; Chromobox protein homolog 5; Antigen p25; Heterochromatin protein 1 homolog alpha

NCBI Accession #

NP_001120793.1;NP_001120794.1;NP_036249.1

Other Accession #

Q61686; NP_036249.1; NP_001120794.1; NP_001120793.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

22225

Recommended Dilutions

WB: 1:1000

CBX5 Antibody (Center) (Cat# 102-12159) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the CBX5 antibody detected the CBX5 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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