Anti-CCDC99 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q96EA4\|Q4R7H3\|NP_060255.3
Gene Id	54908
Gene Symbols	SPDL1
Protein Name / Synonyms	Protein Spindly {ECO:0000255\|HAMAP-Rule:MF_03041}, hSpindly, Arsenite-related gene 1 protein, Coiled-coil domain-containing protein 99 {ECO:0000255\|HAMAP-Rule:MF_03041}, Rhabdomyosarcoma antigen MU-RMS-404A, Spindle apparatus coiled-coil domain-containing protein 1 {ECO:0000255\|HAMAP-Rule:MF_03041}, SPDL1 {ECO:0000255\|HAMAP-Rule:MF_03041}
Clonality	Polyclonal
Clone	RB33449
Isotype	Kappa, Rabbit
Recommended Applications	Western Blotting, IHC-P
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

CCDC99 is required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment.

Other Information

NCBI Accession #

NP_060255.3

Antigen Type

Synthetic Peptide

Format

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Calculated Molecular Weight (Da)

70172

Antigen Source

Human

Images

WB (1:1000)

CCDC99 Antibody (C-term) (Cat. #102-21493) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the CCDC99 antibody detected the CCDC99 protein (arrow).

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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