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Anti-CCND2 (N-term) Antibody
Catalog #: 102-12481
Rabbit Anti-Human CCND2 (N-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P30279 |
| Gene Id | 894 |
| Gene Symbols | CCND2 |
| Protein Name / Synonyms | CCND2 (N-term) |
| Clonality | Polyclonal |
| Preparation | This CCND2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CCND2. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. Knockout studies of the homologous gene in mouse suggest the essential roles of this gene in ovarian granulosa and germ cell proliferation. High level expression of this gene was observed in ovarian and testicular tumors.
Specificity
Other Names
CCND2; G1/S-specific cyclin-D2
NCBI Accession #
NP_001750.1
Other Accession #
NP_001750.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
33067
Recommended Dilutions
WB: 1:1000
 | CCND2 Antibody (N-term) (Cat# 102-12481) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the CCND2 antibody detected the CCND2 protein (arrow). |
 | Western blot analysis of CCND2 (arrow) using rabbit polyclonal CCND2 Antibody (N-term) (Cat# 102-12481). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CCND2 gene. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.