This antibody recognizes the human CD19 cell surface antigen a 96kD single chain glycoprotein on the surface of human B lineage cells, including pre-B cells. B cells can be detected in peripheral blood and tissues. This antibody labels all B lymphocytes in peripheral blood and spleen but is negative on granulocytes, monocytes, platelets, T lymphocytes and erythrocytes.
This antibody is useful for enumerating normal B lymphocytes and typing B cell malignancies by flow cytometry and immunofluorescence.
The antibody reacts with most B cell malignancies including chronic leukaemia and most lymphomas, but not multiple myeloma.
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