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Anti-CD20 Antibody
Catalog #: 188-11468-IHC
Rabbit anti-Human Recombinant CD20 Antibody [IHC only]
Product Description
Specifications
| Size | 7 mL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Specificity | Other species not known |
| Host Species | Rabbit |
| Accession Number | P11836 |
| Gene Id | 931 |
| Gene Symbols | MS4A1,CD20 |
| Protein Name / Synonyms | B-lymphocyte antigen CD20 (B-lymphocyte surface antigen B1) (Bp35) (Leukocyte surface antigen Leu-16) (Membrane-spanning 4-domains subfamily A member 1) (CD antigen CD20) |
| Immunogen | Full length human CD20 protein was used as the immunogen for this reccombinant CD20 antibody. |
| Isotype | IgG, Kappa |
| Purity | Protein A affinity chromatography |
| Concentration (lot specific) | Prediluted in 1X PBS, 0.1 mg/ml BSA (US sourced), 0.05% sodium azide, *For IHC use only* |
| Recommended Applications | Prediluted IHC only format: incubate for 30 min at RT (1) |
| Domain / Region / Terminus | Predominantly cell surface with some cytoplasmic |
| Research Area | Adaptive Immunity |
| Shipping Type | Blue ice |
| Storage | ≤-20°C |
Description
Description
CD20 is expressed on all stages of B cell development except the first and last; it is present from late pro-B cells through memory cells, but not on either early pro-B cells or plasma blasts and plasma cells. It has no known natural ligand and its function is to enable optimal B-cell immune response, specifically against T-independent antigens. It is suspected that it acts as a calcium channel in the cell membrane. It has been shown that CD20 plays a role in the microenvironmental interactions of B cells. [Wiki]
Storage
Recombinant CD20 antibody with azide can be stored at 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
Expiration:
12 months from the date of shipment when stored properly.