RayBiotech

3607 Parkway Ln Ste 200 Norcross, Georgia 30092

www.RayBiotech.com | info@raybiotech.com

770-729-2992 | +1-888-494-8555

ISO 13485:2016 cGMP

Anti-CD243 Antibody

Catalog #: DS-MB-02934

Mouse Anti-Human CD243 (0.1 mg)

Product Description

Specifications

Size0.1 mg
Estimated Lead Time1-2 weeks
SpeciesHuman
Specificity
This product specifically recognizes an extracellular conformational epitope of CD243, also known as MDR1 (multi-drug resistance protein 1) and Pgp (P-glycoprotein), a transmembrane protein and member of the ABC transporter (ATP-binding cassette) family, which acts as an active efflux pump for a diverse range of lipophillic compounds.

CD243 is expressed at low levels in the cell membrane of peripheral blood leucocytes, and constitutively expressed on the apical plasma membrane of excretory epithelial cells of the kidney, liver, brain and small intestine. CD243 mediates resistance to many chemotherapeutic agents used for tumour suppression and is therefore of special interest to oncologists.
Host SpeciesMouse
Protein Name / Synonyms
CD243
Concentration (lot specific)
IgG concentration 1.0mg/ml
Recommended ApplicationsImmunohistology - Frozen, Flow Cytometry, Immunofluorescence, Immunoprecipitation, Immunohistology - Paraffin
Research AreaAdaptive Immunity
Shipping TypeBlue ice
Storage-20°C

Description

Storage/Stability

Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Format Type:
Purified

Preparation

Immunogen:
Mouse Balb/c 3T3 fibroblasts transfected with human CD243 cDNA.
Preservative:
0.09%Sodium Azide (NaN3)
Expiration:
12 months from the date of shipment when stored properly.