Anti-CD284 Antibody

Catalog #: DS-MB-00578

Mouse Anti-Human CD284 (0.5 mg)

Product Description

Specifications

Size	0.5 mg
Estimated Lead Time	1-2 weeks
Species	Human
Specificity	This product recognizes the human Toll like receptor 4 (TLR4) cell surface antigen. TLR4, also known as CD284, has been demonstrated to act as a receptor for LPS on human monocytes and macrophages. TLR4 signalling of LPS stimulation requires the presence of the MD-2 molecule. TLR4 is weakly expressed by resting cells, but is upregulated following stimulation with LPS. This antibody has been demonstrated to block activation of monocytes with LPS.
Host Species	Mouse
Protein Name / Synonyms	CD284
Concentration (lot specific)	IgG concentration 1.0 mg/ml
Recommended Applications	Flow Cytometry, Functional Assays, Immunoprecipitation, Western Blotting
Research Area	Adaptive Immunity
Shipping Type	Blue ice
Storage	-20°C

Description

Storage/Stability

Store at -20 °C only.

This product should be stored undiluted.

Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:

Purified IgG - liquid

Formulation:

Phosphate buffered saline

Quality Control (Contaminants):

<0.01 EU/ug

Format Type:

Low Endotoxin

Preparation

Immunogen:

Ba/F3 cell line expressing TLR4 (CD284).

Preservative:

None present

This product

Spleen cells from immunised Balb/c mice were fused with cells of the mouse SP2/0 myeloma cell line.

Expiration:

12 months from the date of shipment when stored properly.

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