Anti-CD320 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q9NPF0
Gene Id	51293
Gene Symbols	CD320
Protein Name / Synonyms	CD320 (C-term)
Clonality	Polyclonal
Preparation	This CD320 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 153-182 amino acids from the C-terminal region of human CD320.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting
Research Area	Adaptive Immunity
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

The CD320 antigen gene encodes the transcobalamin receptor (TCBLR). Cellular uptake of cobalamin (vitamin B12) is mediated by receptors expressed on the cell surface. Transcobalamin II (TCN2; MIM 613441), a plasma protein secreted by endothelial cells, binds the cobalamin absorbed in the distal ileum and carries 10 to 30% of total circulating cobalamin. CD320 encodes a transcobalamin receptor that binds TCN2-cobalamin at the plasma membrane and internalizes the complex by endocytosis (Quadros et al., 2009 [PubMed 18779389]).

Specificity

Other Names

CD320; 8D6A; CD320 antigen; 8D6 antigen; FDC-signaling molecule 8D6; Transcobalamin receptor; CD_antigen=CD320; Flags: Precursor

NCBI Accession #

NP_001159367.1;NP_057663.1

Other Accession #

NP_001159367.1; NP_057663.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

28991

Recommended Dilutions

WB: 1:1000

CD320 Antibody (C-term) (Cat# 102-11882) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the CD320 antibody detected the CD320 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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