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Anti-CD33 (Center) Antibody
Catalog #: 102-12048
Rabbit Anti-Human CD33 (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P20138 |
| Gene Id | 945 |
| Gene Symbols | CD33 |
| Protein Name / Synonyms | CD33 (Center) |
| Clonality | Polyclonal |
| Preparation | This CD33 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-117 amino acids from the Central region of human CD33. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting |
| Research Area | Cancer, Adaptive Immunity |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro).
Specificity
Other Names
CD33; SIGLEC3; Myeloid cell surface antigen CD33; Sialic acid-binding Ig-like lectin 3; gp67; CD_antigen=CD33; Flags: Precursor
NCBI Accession #
NP_001076087.1;NP_001171079.1;NP_001763.3
Other Accession #
NP_001763.3
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
39825
Recommended Dilutions
WB: 1:1000
 | CD33 Antibody (Center) (Cat# 102-12048) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the CD33 antibody detected the CD33 protein (arrow). |
 | Western blot analysis of CD33 (arrow) using rabbit polyclonal CD33 Antibody (Center) (Cat# 102-12048). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CD33 gene. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.