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Anti-CD34 Antibody, PE
Catalog #: 188-10041-PE
Mouse anti-Human/Rat CD34 Antibody [PE Conjugated]
Product Description
Specifications
| Size | 100 tests |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Rat |
| Specificity | Other species not known |
| Host Species | Mouse |
| Accession Number | P28906 |
| Gene Id | 947 |
| Gene Symbols | CD34 |
| Protein Name / Synonyms | Hematopoietic progenitor cell antigen CD34 (CD antigen CD34) |
| Immunogen | Blast cells from a chronic myeloid leukemia patient were used as the immunogen for this CD34 antibody. |
| Isotype | Kappa, IgG1 |
| Purity | Protein G affinity chromatography |
| Concentration (lot specific) | 500 ul at 0.1 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide |
| Recommended Applications | Flow Cytometry: 5ul per test per one million cells in 0.1ml (or 5ul per 100ul of whole blood) Immunofluorescence: 1:50-1:100 |
| Domain / Region / Terminus | Cell surface |
| Research Area | Angiogenesis, Adaptive Immunity |
| Shipping Type | Blue ice |
| Storage | 2-8°C |
Description
Description
This antibody recognizes a single chain, transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34. Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, it is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. CD34 expression is also found in vascular endothelium. Additionally, it appears that proliferating endothelial cells overexpress this molecule than the non-proliferating endothelial cells. Anti-CD34 labels > 85% of angiosarcoma and Kaposis sarcoma, but shows low specificity.
Storage
Store the CD34 antibody at 2-8°C. Conjugate is light sensitive, store in the dark.
Expiration:
12 months from the date of shipment when stored properly.