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Anti-CD43 Antibody
Catalog #: 188-11238-IHC
Rabbit anti-Human Recombinant CD43 Antibody [IHC only]
Product Description
Specifications
| Size | 7 mL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Specificity | Other species not tested. |
| Host Species | Rabbit |
| Accession Number | P16150 |
| Gene Id | 6693 |
| Gene Symbols | SPN,CD43 |
| Protein Name / Synonyms | Leukosialin (Galactoglycoprotein) (GALGP) (Leukocyte sialoglycoprotein) (Sialophorin) (CD antigen CD43) |
| Immunogen | Recombinant human protein was used as the immunogen for the recombinant CD43 antibody. |
| Isotype | IgG, Kappa |
| Purity | Protein A affinity chromatography |
| Concentration (lot specific) | Prediluted in 1X PBS, 0.1 mg/ml BSA (US sourced), 0.05% sodium azide, *For IHC use only* |
| Recommended Applications | Prediluted IHC only format: incubate for 30 min at RT (1) |
| Domain / Region / Terminus | Cell surface |
| Research Area | Cancer, Adaptive Immunity |
| Shipping Type | Blue ice |
| Storage | ≤-20°C |
Description
Description
It recognizes a cell surface glycoprotein of 95/115/135kDa (depending upon the extent of glycosylation), identified as CD43. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma.
Storage
Store the recombinant CD43 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Expiration:
12 months from the date of shipment when stored properly.