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Anti-CD70 (Center) Antibody
Catalog #: 102-12628
Rabbit Anti-Human CD70 (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P32970 |
| Gene Id | 970 |
| Gene Symbols | CD70 |
| Protein Name / Synonyms | CD70 (Center) |
| Clonality | Polyclonal |
| Preparation | This CD70 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 72-101 amino acids from the Central region of human CD70. |
| Concentration (lot specific) | 0.500 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Research Area | Cancer, Adaptive Immunity |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.
Specificity
Other Names
CD70; CD27L; CD27LG; TNFSF7; CD70 antigen; CD27 ligand; Tumor necrosis factor ligand superfamily member 7; CD_antigen=CD70
NCBI Accession #
NP_001243.1
Other Accession #
NP_001243.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
21118
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
 | CD70 Antibody (Center) (Cat# 102-12628) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the CD70 antibody detected the CD70 protein (arrow). |
 | CD70 Antibody (Center) (102-12628)immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CD70 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.