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Anti-CD86 Antibody, PE
Catalog #: 188-10036-PE
Mouse anti-Human/Mouse/Rat CD86 Antibody [PE Conjugated]
Product Description
Specifications
| Size | 100 tests |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse, Rat |
| Specificity | Other species not known |
| Host Species | Mouse |
| Accession Number | P42081 |
| Gene Id | 942 |
| Gene Symbols | CD86,CD28LG2 |
| Protein Name / Synonyms | T-lymphocyte activation antigen CD86 (Activation B7-2 antigen) (B70) (BU63) (CTLA-4 counter-receptor B7.2) (FUN-1) (CD antigen CD86) |
| Immunogen | ARH-77 (B-lymphoblastoid cell line) was used as the immunogen for this CD86 antibody. |
| Isotype | Kappa, IgG1 |
| Purity | Protein G affinity chromatography |
| Concentration (lot specific) | 500 ul at 0.1 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide |
| Recommended Applications | FACS: 5ul/test/10^6 cells IF: 1:50-1:100 |
| Domain / Region / Terminus | Cell surface |
| Research Area | Adaptive Immunity |
| Shipping Type | Blue ice |
| Storage | 2-8°C |
Description
Description
This antibody recognizes a protein of 70kDa, which is identified as CD86 (HLDA V; WS Code BP BP072. HLDA V; WS Code A A109. HLDA VI; WS Code BP 95. HLDA VI; WS Code B CD86.9). CD86 is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density on resting B and T lymphocytes. CD86 expression is rapidly upregulated by B cell specific stimuli with peak expression at 18 to 42 hours after stimulation. CD86, along with CD80/B71, is an important accessory molecule in T cell co-stimulation via its interaction with CD28 and CD152/CTLA4. Since CD86 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response. It is also found on malignant Hodgkin and Reed Sternberg (HRS) cells in Hodgkin's disease.
Storage
Store the CD86 antibody PE conjugate at 2-8°C. The conjugate is light-sensitive, protect from light.
Expiration:
12 months from the date of shipment when stored properly.