Anti-CD86 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P42081
Gene Id	942
Gene Symbols	CD86
Protein Name / Synonyms	CD86 (C-term)
Clonality	Polyclonal
Preparation	This CD86 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 269-298 amino acids from the C-terminal region of human CD86.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting
Research Area	Adaptive Immunity
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined. [provided by RefSeq].

Specificity

Other Names

CD86; CD28LG2; T-lymphocyte activation antigen CD86; Activation B7-2 antigen; B70; BU63; CTLA-4 counter-receptor B7.2; FUN-1; CD_antigen=CD86; Flags: Precursor

NCBI Accession #

NP_001193853.1;NP_001193854.1;NP_008820.3;NP_787058.4;NP_795711.1

Other Accession #

NP_008820.2; NP_787058.3

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

37682

Recommended Dilutions

WB: 1:1000

CD86 Antibody (C-term) (Cat# 102-12852) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the CD86 antibody detected the CD86 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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