Anti-CD8B (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P10966
Gene Id	926
Gene Symbols	CD8B
Protein Name / Synonyms	CD8B (N-term)
Clonality	Polyclonal
Preparation	This CD8B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 64-92 amino acids from the N-terminal region of human CD8B.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting, FC
Research Area	Adaptive Immunity
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.

Specificity

Other Names

CD8B; CD8B1; T-cell surface glycoprotein CD8 beta chain; CD_antigen=CD8b; Flags: Precursor

NCBI Accession #

NP_001171571.1;NP_004922.1;NP_742099.1;NP_742100.1;NP_757362.1

Other Accession #

A6NJW9

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

23722

Recommended Dilutions

WB: 1:1000; FC: 1:10-50

	Western blot analysis of anti-CD8B1 Pab (Cat# 102-12474) in K562 cell line lysates (35ug/lane). CD8B1(arrow) was detected using the purified Pab.
	Flow cytometric analysis of jurkat cells using CD8B Antibody (N-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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