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Anti-Cdc14 Antibody
Catalog #: 102-17876
Rabbit Anti-Cdc14 Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | Q9UNH5 |
| Gene Id | 8556 |
| Gene Symbols | CDC14A |
| Protein Name / Synonyms | Cdc14 |
| Clonality | Polyclonal |
| Preparation | This Cdc14 antibody is generated from rabbits immunized with a recombinant protein encoding aa 1~379 of human cdc14. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting, IHC-P, FC |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms.
Specificity
Other Names
CDC14A; Dual specificity protein phosphatase CDC14A; CDC14 cell division cycle 14 homolog A
NCBI Accession #
NP_003663.2;NP_201569.1;NP_201570.1
Other Accession #
NP_003663
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
66574
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50; FC: 1:10-50
 | His6-cdc14 Antibody (Cat# 102-17876) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the cdc14 antibody detected the cdc14 protein (arrow). |
 | Cdc14 Antibody (Cat# 102-17876)immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Cdc14 Antibody for immunohistochemistry. Clinical relevance has not been evaluated. |
 | Cdc14 Antibody (Cat# 102-17876) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.