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Anti-CDC37 (Center) Antibody
Catalog #: 102-18098
Rabbit Anti-Human CDC37 (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q16543 |
| Gene Id | 11140 |
| Gene Symbols | CDC37 |
| Protein Name / Synonyms | CDC37 (Center) |
| Clonality | Polyclonal |
| Preparation | This CDC37 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 116-144 amino acids from the Central region of human CDC37. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting, IHC-P, FC |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
CDC37 is a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases.
Specificity
Other Names
CDC37; CDC37A; Hsp90 co-chaperone Cdc37; Hsp90 chaperone protein kinase-targeting subunit; p50Cdc37
NCBI Accession #
NP_008996.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
44468
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100; FC: 1:10-50
 | Western blot analysis of CDC37 Antibody (Center) (Cat# 102-18098) in MCF-7, A2058 cell line lysates (35ug/lane). CDC37 (arrow) was detected using the purified Pab. |
 | CDC37 Antibody (Center) (Cat# 102-18098) IHC analysis in formalin fixed and paraffin embedded skin followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CDC37 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. |
 | CDC37 Antibody (Center) (Cat# 102-18098) flow cytometric analysis of MCF-7 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.