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Anti-CDC42EP2 (C-term) Antibody

Catalog #: 102-13292

Rabbit Anti-CDC42EP2 (C-term) Antibody, 400 ul

Product Description

Specifications

Size400 µL
Estimated Lead Time1-2 weeks
SpeciesHuman, Mouse
Host SpeciesRabbit
Accession Number
O14613
Gene Id
10435
Gene Symbols
CDC42EP2
Protein Name / Synonyms
CDC42EP2 (C-term)
ClonalityPolyclonal
PreparationThis CDC42EP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 133-160 amino acids from the C-terminal region of human CDC42EP2.
Concentration (lot specific)
0.300 mg/ml
Recommended ApplicationsWestern Blotting
Shipping TypeBlue ice
Storage-20°C

Description

Introduction

CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of, CDC42. Coexpression of this protein with dominant negative mutant CDC42 protein in fibroblast was found to induce pseudopodia formation, which suggested a role of this protein in actin filament assembly and cell shape control.

Specificity

Other Names
CDC42EP2; BORG1; CEP2; Cdc42 effector protein 2; Binder of Rho GTPases 1
NCBI Accession #
NP_006770.1
Other Accession #
NP_006770.1

Format

Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
22484
Recommended Dilutions
WB: 1:1000
CDC42EP2 Antibody (C-term) (Cat# 102-13292) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the CDC42EP2 antibody detected the CDC42EP2 protein (arrow).
CDC42EP2 Antibody (C-term) (Cat# 102-13292) western blot analysis in mouse stomach tissue lysates (35ug/lane).This demonstrates the CDC42EP2 antibody detected the CDC42EP2 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.