Anti-Cdc6 (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q99741
Gene Id	990
Gene Symbols	CDC6
Protein Name / Synonyms	Cdc6 (N-term)
Clonality	Polyclonal
Preparation	This Cdc6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 32-61 amino acids from the N-terminal region of human Cdc6.
Concentration (lot specific)	0.430 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Human Cdc6 is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins.

Specificity

Other Names

CDC6; CDC18L; Cell division control protein 6 homolog; CDC6-related protein; Cdc18-related protein; p62(cdc6)

NCBI Accession #

NP_001245.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

62720

Recommended Dilutions

WB: 1:1000

Western blot analysis of Cdc6 Antibody (N-term)(Cat# 102-16713) in Romas cell line lysates (35ug/lane). Cdc6 (arrow) was detected using the purified Pab.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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