Anti-CDH20 (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q9HBT6
Gene Id	28316
Gene Symbols	CDH20
Protein Name / Synonyms	CDH20 (N-term)
Clonality	Polyclonal
Preparation	This CDH20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 111-140 amino acids from the N-terminal region of human CDH20.
Concentration (lot specific)	0.370 mg/ml
Recommended Applications	Western Blotting, IHC-P, FC
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene is a type II classical cadherin from the cadherin superfamily and one of three cadherin 7-like genes located in a cluster on chromosome 18. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Since disturbance of intracellular adhesion is a prerequisite for invasion and metastasis of tumor cells, cadherins are considered prime candidates for tumor suppressor genes.

Specificity

Predicted Reactivity

Mouse, Rat

Other Names

CDH20; CDH7L3; Cadherin-20

NCBI Accession #

NP_114097.2

Other Accession #

Q5DWV1; Q9Z0M3

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

88993

Recommended Dilutions

WB: 1:1000; IHC: 1:50-100; FC: 1:10-50

	Western blot analysis of CDH20 Antibody (N-term) (Cat# 102-18426) in HepG2 cell line lysates (35ug/lane). CDH20 (arrow) was detected using the purified Pab.
	CDH20 Antibody (N-term) (Cat# 102-18426) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CDH20 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
	CDH20 Antibody (N-term) (Cat# 102-18426) flow cytometric analysis of HepG2 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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