Anti-CDK2 (T14) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P24941
Gene Id	1017
Gene Symbols	CDK2
Protein Name / Synonyms	CDK2 (T14)
Clonality	Polyclonal
Preparation	This CDK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from human CDK2.
Concentration (lot specific)	0.290 mg/ml
Recommended Applications	Western Blotting, IHC-P
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

CDK2 is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and is regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation.

Specificity

Predicted Reactivity

Mouse, Rat, Bovine, Hamster, Xenopus

Other Names

CDK2; CDKN2; Cyclin-dependent kinase 2; Cell division protein kinase 2; p33 protein kinase

NCBI Accession #

NP_001789.2;NP_439892.2

Other Accession #

Q80YP0; Q00526; P23437; Q63699; P97377; O55076; Q5E9Y0

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

33930

Recommended Dilutions

WB: 1:1000; IHC: 1:10-50

	Cdk2 Antibody (T14) (Cat# 102-17402) western blot analysis in 293,Hela cell line lysates (35ug/lane).This demonstrates the hCdk2 antibody detected the hCdk2 protein (arrow).
	Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with CDK2 Antibody (T14) (Cat# 102-17402), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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