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Product Description
Specifications
| Size | 0.1 mL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Accession Number | P49918 |
| Gene Id | 1028 |
| Gene Symbols | CDKN1C |
| Protein Name / Synonyms | CDKN1C (Ascites) |
| Clonality | Monoclonal |
| Preparation | This CDKN1C antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 34-64 amino acids from human CDKN1C. |
| Recommended Applications | Western Blotting |
| Research Area | Cancer |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.
Specificity
Other Names
CDKN1C; KIP2; Cyclin-dependent kinase inhibitor 1C; Cyclin-dependent kinase inhibitor p57; p57Kip2
NCBI Accession #
NP_000067.1;NP_001116102.1;NP_001116103.1
Other Accession #
NP_000067.1
Format
Type
Mouse Monoclonal Antibody (Mab)
Calculated Molecular Weight (Da)
32177
Recommended Dilutions
WB: 1:500-16000
 | CDKN1C Antibody (Cat# 102-10303) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the CDKN1C antibody detected the CDKN1C protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.