Anti-CDKN2A Antibody

Product Description

Specifications

Size	0.1 mg
Estimated Lead Time	1-2 weeks
Species	Human
Specificity	This product recognizes human cyclin-dependent kinase inhibitor 2A (CDKN2A), a 16kDa protein belonging to the CDKN2 cyclin dependent kinase inhibitor family. CDKN2A acts as a negative regulator of cell proliferation by interacting strongly with CDK4 and CDK6, thus inhibiting their ability to interact with cyclin D and to phosphorylate the retinoblastoma protein. CDKN2A is an important tumour suppressor and defects in its production results in tumour formation in a wide range of tissues, including cutaneous malignant melanoma and Li-Fraumeni syndrome.
Host Species	Rabbit
Protein Name / Synonyms	CDKN2A
Preparation	Antiserum to human CDKN2A was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Recommended Applications	Immunohistology - Paraffin, Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

This product detects a band of approximately 20 kDa in mouse colon cell lysates.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:

Purified IgG - liquid

Formulation:

Phosphate buffered saline

Format Type:

Purified

Preparation

Antiserum to human CDKN2A was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.

Immunogen:

A 19 amino acid peptide located near the amino terminus of human CDKN2A.

Preservative:

0.02% Sodium Azide (NaN₃)

Expiration:

12 months from the date of shipment when stored properly.

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