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Anti-CDw328 Antibody
Catalog #: DS-MB-03268
Mouse Anti-Human CDw328 (0.1 mg)
Product Description
Specifications
| Size | 0.1 mg |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Specificity | This product is specific for human CDw328, a type I transmembrane glycoprotein and member of the Siglec (sialic acid binding Ig-like lectin) family, designated Siglec-7, originally identified as an inhibitory NK cell receptor (NKR) and negative regulator of NK activation, attributed to ITIM recruitment of SHP-1 phosphatase. CDw328 is expressed predominantly by natural killer cells (NK) and to a lesser extent by monocytes and granulocytes and, like Siglec-5 (CD170), has been shown to bind to sialylated ligands of targets through recognition of sialic acid in both the alpha-2,3- and alpha-2,6- glycosidic linkage. |
| Host Species | Mouse |
| Protein Name / Synonyms | CDw328 |
| Concentration (lot specific) | IgG concentration 1.0mg/ml |
| Recommended Applications | Immunohistology - Frozen, Flow Cytometry |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Storage/Stability
Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Format
Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Format Type:
Purified
Preparation
Immunogen:
Monocyte-derived dendritic cells
Preservative:
0.09% Sodium Azide (NaN3)
This product
Spleen cells from immunised Balb/c mice were fused with cells of the X63-Ag8.653 myeloma cell line.
Expiration:
12 months from the date of shipment when stored properly.