This product recognizes the human serum complement protein factor H (155kD), binding to a different epitope from MRC OX-23. This antibody also recognizes a 43-49kD truncated form of factor H present at low level (1-5 ug/ml) in plasma and urine. In an immunoprecipitation system, it recognizes factor H in other primates, but not in cow, sheep, pig, chicken or rabbit sera.
This antibody inhibits the binding of factor H to surface bound C3b, and recognizes Factor H in Western blotting procedures.
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