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Anti-CFHR5 (Center) Antibody
Catalog #: 102-16559
Rabbit Anti-Human CFHR5 (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q9BXR6 |
| Gene Id | 81494 |
| Gene Symbols | CFHR5 |
| Protein Name / Synonyms | CFHR5 (Center) |
| Clonality | Polyclonal |
| Preparation | This CFHR5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 203-231 amino acids from the Central region of human CFHR5. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting, IHC-P, FC |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
CFHR5 is a member of a small complement factor H (CFH) gene cluster on chromosome 1. Each member of this gene family contains multiple short consensus repeats (SCRs) typical of regulators of complement activation. The protein encoded by this gene has nine SCRs with the first two repeats having heparin binding properties, a region within repeats 5-7 having heparin binding and C reactive protein binding properties, and the C-terminal repeats being similar to a complement component 3 b (C3b) binding domain. This protein co-localizes with C3, binds C3b in a dose-dependent manner, and is recruited to tissues damaged by C-reactive protein. Allelic variations in this gene have been associated, but not causally linked, with two different forms of kidney disease: membranoproliferative glomerulonephritis type II (MPGNII) and hemolytic uraemic syndrome (HUS). [provided by RefSeq].
Specificity
Other Names
CFHR5; CFHL5; FHR5; Complement factor H-related protein 5
NCBI Accession #
NP_110414.1
Other Accession #
NP_110414.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
64419
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50; FC: 1:10-50
 | CFHR5 Antibody (Center) (Cat# 102-16559) western blot analysis in CEM(lane 1),K562(lane 2) cell line lysates (15ug/lane).This demonstrates the CFHR5 antibody detected the CFHR5 protein (arrow). |
 | CFHR5 Antibody (Center) (Cat# 102-16559) immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CFHR5 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. |
 | CFHR5 Antibody (Center) (Cat# 102-16559) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.