3607 Parkway Ln Ste 200 Norcross, Georgia 30092
www.RayBiotech.com | info@raybiotech.com
770-729-2992 | +1-888-494-8555
ISO 13485:2016 cGMP
Anti-CHMP2B (N-term) Antibody
Catalog #: 102-11952
Rabbit Anti-Human CHMP2B (N-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q9UQN3 |
| Gene Id | 25978 |
| Gene Symbols | CHMP2B |
| Protein Name / Synonyms | CHMP2B (N-term) |
| Clonality | Polyclonal |
| Preparation | This CHMP2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CHMP2B. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Research Area | Autophagy |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
This gene encodes a component of the heteromeric ESCRT-III complex (Endosomal Sorting Complex Required for Transport III) that functions in the recycling or degradation of cell surface receptors. ESCRT-III functions in the concentration and invagination of ubiquitinated endosomal cargos into intralumenal vesicles. The protein encoded by this gene is found as a monomer in the cytosol or as an oligomer in ESCRT-III complexes on endosomal membranes. It is expressed in neurons of all major regions of the brain. Mutations in this gene result in one form of familial frontotemporal lobar degeneration.
Specificity
Predicted Reactivity
Mouse, Bovine
Other Names
CHMP2B; Charged multivesicular body protein 2b; CHMP2.5; Chromatin-modifying protein 2b; Vacuolar protein sorting-associated protein 2-2
NCBI Accession #
NP_001231573.1;NP_054762.2
Other Accession #
Q8BJF9; Q3SX42; NP_054762.2
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
23907
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
 | CHMP2B Antibody (N-term) (Cat# 102-11952) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the CHMP2B antibody detected the CHMP2B protein (arrow). |
 | CHMP2B Antibody (N-term) (Cat# 102-11952)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CHMP2B Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.