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Anti-CHRM2 (Center) Antibody
Catalog #: 102-12480
Rabbit Anti-Human CHRM2 (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P08172 |
| Gene Id | 1129 |
| Gene Symbols | CHRM2 |
| Protein Name / Synonyms | CHRM2 (Center) |
| Clonality | Polyclonal |
| Preparation | This CHRM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 336-364 amino acids from the Central region of human CHRM2. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting |
| Research Area | Cardiovascular Disease |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene.
Specificity
Predicted Reactivity
Mouse, Rat, Bovine, Pig
Other Names
CHRM2; Muscarinic acetylcholine receptor M2
NCBI Accession #
NP_000730.1;NP_001006627.1;NP_001006628.1;NP_001006629.1;NP_001006630.1;NP_001006631.1;NP_001006632.1;NP_001006633.1
Other Accession #
P10980; P06199; Q9ERZ4; P41985; NP_000730.1; NP_001006628.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
51715
Recommended Dilutions
WB: 1:1000
 | CHRM2 Antibody (Center) (Cat# 102-12480) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the CHRM2 antibody detected the CHRM2 protein (arrow). |
 | Western blot analysis of CHRM2 (arrow) using rabbit polyclonal CHRM2 Antibody (Center) (Cat# 102-12480). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CHRM2 gene. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.