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Anti-CHRNA10 (Center) Antibody
Catalog #: 102-11434
Rabbit Anti-Human CHRNA10 (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q9GZZ6 |
| Gene Id | 57053 |
| Gene Symbols | CHRNA10 |
| Protein Name / Synonyms | CHRNA10 (Center) |
| Clonality | Polyclonal |
| Preparation | This CHRNA10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 179-206 amino acids from the Central region of human CHRNA10. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | IHC-P, Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
CHRNA10 is an ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma.
Specificity
Predicted Reactivity
Rat
Other Names
CHRNA10; NACHRA10; Neuronal acetylcholine receptor subunit alpha-10; Nicotinic acetylcholine receptor subunit alpha-10
NCBI Accession #
NP_065135.2
Other Accession #
Q9JLB5; NP_065135.2
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
49705
Recommended Dilutions
IHC: 1:10-50; WB: 1:1000
 | CHRNA10 Antibody (Center) (Cat# 102-11434)immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CHRNA10 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. |
 | CHRNA10 Antibody (Center) (Cat# 102-11434) western blot analysis in NCI-H292,MDA-MB453,ZR-75-1 cell line lysates (35ug/lane).This demonstrates the CHRNA10 antibody detected the CHRNA10 protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.