Anti-CKMT2 (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P17540
Gene Id	1160
Gene Symbols	CKMT2
Protein Name / Synonyms	CKMT2 (N-term)
Clonality	Polyclonal
Preparation	This CKMT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 56-86 amino acids from the N-terminal region of human CKMT2.
Concentration (lot specific)	2.0 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80% homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis.

Specificity

Other Names

CKMT2; Creatine kinase S-type, mitochondrial; Basic-type mitochondrial creatine kinase; Sarcomeric mitochondrial creatine kinase

NCBI Accession #

NP_001093205.1;NP_001093206.1;NP_001816.2

Format

Type

Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

47504

Recommended Dilutions

WB: 1:1000

	Western blot analysis of lysates from human skeletal muscle and heart tissue lysates (from left to right), using CKMT2 Antibody (A71)(Cat# 102-17110). 102-17110 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.
	Western blot analysis of lysate from human heart tissue lysate, using CKMT2 Antibody ?A71?(Cat# 102-17110). 102-17110 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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