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Anti-CLASP2 (C-term) Antibody

Catalog #: 102-17164

Rabbit Anti-Human CLASP2 (C-term) Antibody, 400 ul

Product Description

Specifications

Size400 µL
Estimated Lead Time1-2 weeks
SpeciesHuman
Host SpeciesRabbit
Accession Number
O75122
Gene Id
23122
Gene Symbols
CLASP2
Protein Name / Synonyms
CLASP2 (C-term)
ClonalityPolyclonal
PreparationThis CLASP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 946-975 amino acids from the C-terminal region of human CLASP2.
Concentration (lot specific)
0.410 mg/ml
Recommended ApplicationsWestern Blotting, IHC-P
Shipping TypeBlue ice
Storage-20°C

Description

Introduction

Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle.

Specificity

Other Names
CLASP2; KIAA0627; CLIP-associating protein 2; Cytoplasmic linker-associated protein 2; Protein Orbit homolog 2
NCBI Accession #
NP_001193973.1;NP_055912.2
Other Accession #
NP_055912

Format

Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
141133
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100
Western blot analysis of anti-CLASP2 Antibody (C-term) (Cat# 102-17164) in mouse kidney tissue lysates (35ug/lane). CLASP2(arrow) was detected using the purified Pab.
Formalin-fixed and paraffin-embedded human Hepatocellular carcinoma reacted with anti-CLASP2 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.