Anti-CLASP2 (Y1019) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse
Host Species	Rabbit
Accession Number	O75122\|Q99JD4\|Q8BRT1
Gene Id	23122
Gene Symbols	CLASP2
Protein Name / Synonyms	CLIP-associating protein 2, Cytoplasmic linker-associated protein 2, Protein Orbit homolog 2, hOrbit2, CLASP2, KIAA0627
Clonality	Polyclonal
Clone	RB16644
Isotype	Kappa, Rabbit
Recommended Applications	Western Blotting, FC
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

CLASP2 is microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle.

Other Information

NCBI Accession #

NP_001193973.1;NP_055912.2

Antigen Type

Synthetic Peptide

Format

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Calculated Molecular Weight (Da)

141064

Antigen Source

Human

Images

WB (1:1000)

Western blot analysis of CLASP (arrow) using rabbit polyclonal CLASP Antibody (Y1019) (Cat. #102-27647). 293 cell lysates transfected with the ACADL gene (Lane 1) and with the GFP-CLASP (Lane 2).

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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