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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P57739 |
| Gene Id | 9075 |
| Gene Symbols | CLDN2 |
| Protein Name / Synonyms | CLDN2 (C-term Y195) |
| Clonality | Polyclonal |
| Preparation | This CLDN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 174-201 amino acids from the C-terminal region of human CLDN2. |
| Concentration (lot specific) | 0.300 mg/ml |
| Recommended Applications | Western Blotting, IHC-P, FC |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. This protein is expressed in the intestine. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene.
Specificity
Other Names
CLDN2; Claudin-2; SP82
NCBI Accession #
NP_001164563.1;NP_001164566.1;NP_065117.1
Other Accession #
NP_001164566.1; NP_065117.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
24549
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50; FC: 1:10-50
 | Western blot analysis of CLDN2 (arrow) using rabbit polyclonal CLDN2 Antibody (Y195) (Cat# 102-11665). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CLDN2 gene. |
 | CLDN2 Antibody (C-term Y195) (Cat# 102-11665)immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CLDN2 Antibody (C-term Y195) for immunohistochemistry. Clinical relevance has not been evaluated. |
 | CLDN2 Antibody (C-term Y195) (Cat# 102-11665) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.