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Anti-CLU / ApoJ Antibody
Catalog #: DS-PB-00501
Rabbit Anti-Human CLU / ApoJ
Product Description
Specifications
| Size | 0.1 mg |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Specificity | This product recognizes human clusterin (also known as apolipoprotein J). Clusterin is a ubiquitous glycoprotein which exists in at least two distinct isoforms; a proapoptotic nuclear form, of 49kDa, and a prosurvival secretory form with a molecular weight of 75-80kDa. Clusterin is implicated in several diverse physiological processes including sperm maturation, cell differentiation, and apoptosis. Clusterin upregulation has been reported in various human malignancies, including bladder, prostate, and breast tumours. Following specific stress induced injury, secretory clusterin acts as a molecular chaperone, scavenging denatured proteins outside cells. It has been shown to be upregulated in Alzheimer's disease, retinitis pigmentosa, glomerulonephritis, atherosclerosis and myocardial infarction. |
| Host Species | Rabbit |
| Protein Name / Synonyms | CLU / ApoJ |
| Preparation | Antisera to Clusterin were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography. |
| Concentration (lot specific) | IgG concentration 1.0mg/ml |
| Recommended Applications | Immunohistology - Paraffin, Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
This product detects a band of approximately 60kDa in human brain tissue lysate.
Storage/Stability
Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Format
Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Format Type:
Purified
Preparation
Antisera to Clusterin were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.
Immunogen:
Recombinant human clusterin isoform 1.
Preservative:
| 0.02% | Sodium Azide (NaN3) |
Expiration:
12 months from the date of shipment when stored properly.