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Anti-CMKLR1 Antibody
Catalog #: 102-25677
Rabbit Anti-CMKLR1 Antibody, 100 µl
Product Description
Specifications
| Size | 100 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse, Rat |
| Host Species | Rabbit |
| Accession Number | Q99788 |
| Gene Id | 1240 |
| Gene Symbols | CMKLR1 |
| Protein Name / Synonyms | Chemokine-like receptor 1, G-protein coupled receptor ChemR23, G-protein coupled receptor DEZ, CMKLR1, CHEMR23, DEZ |
| Clonality | Polyclonal |
| Recommended Applications | Western Blotting |
| Research Area | Inflammation |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 induces activation of intracellular signaling molecules, such as SKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifunctional effects, like, reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF- kappa-B. Positively regulates adipogenesis and adipocyte metabolism. Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2).
Other Information
Antigen Type
Synthetic Peptide
Images
WB ( 1:1000)
Western blot analysis of lysates from Hela,HUVEC cell line (from left to right),using CMKLR1 Antibody(102-25677). 102-25677 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysates at 35ug per lane.
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.